I am back...
i did receive a new GPSberry card.
i try first on a PI3, i plugged it and to configured it. GREAT !!! now it is working (see the image attach)
OK my new GPSberry is operational.
Now i go back to my new PI4 and unfortunatly this is the same issue , with strange characters (with minicom or with cat /dev/serial0).
even if i try to upgrade again the Raspbian , this is the same issue
Do you have any clues ?